Evaluation of the toxicity of the individual chemical ingredients of the formulation used to manufacture the product:
Each ingredient is assessed for its hazard or “inherent” toxicity such as acute toxicity, skin/eye irritancy, potential for skin sensitization, reproductive, genotoxic, or carcinogenic activity, in relation to the potential for consumer exposure to the chemical
Potential for synergistic or unpredictable adverse effects from the combination of ingredients in the formulation
Exposure considerations:
characteristics of the product such as physical form and size/volume
accessibility (e.g. liquid components)
intended use
Consideration of potential for misuse of the product
Packaging compliance guidance and advice on mandatory label requirements
